GWAS Strategy
GWAS was run using MLM model in GCTA1.93.2. The phenotypes were pre-adjusted by age, sex, and 20 PCs
Probands
All Individuals
- 6,558,644 QCd SNPs with MAF > 0.01 included
- GWAS was run on all individuals (ranging from 5628 to 6595) including diverse ancestry backgrounds.
- Signals with association p-value < 1e-5 will be shown for Manhattan Plots.
QQ Plot

Manhattan Plot

Europeans Only
- ~5K European individuals are included
- Signals with association p-value < 1e-5 will be shown for Manhattan Plots.
QQ Plot

Manhattan Plot
